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How to Deep Clean Your Memory Foam Mattress: A Guide to Healthier Sleep

by Lcora on November 11, 2025

When was the last time you gave your mattress a serious cleaning? Most people don't realize that their memory foam mattress becomes a breeding ground for bacteria, dust, and allergens with each passing night. Professional cleaning isn't just about making your mattress look good—it's about creating a healthier sleep environment that supports your overall well-being and protects your valuable investment. Understanding the components of your bed is the first step, and you can learn more about what's inside a memory foam mattress here.

Ventura memory foam mattress on beige bed frame with tufted headboard in bedroom.

What Makes Memory Foam Mattresses Different from Other Mattresses?

Not all mattresses clean the same way. Memory foam needs special care because it absorbs moisture like a sponge and can be easily damaged by water or harsh cleaners.

 

What to Consider Memory Foam Innerspring Latex Hybrid

Can I use water?

Very Little Only

Yes

Yes (Moderate)

Limited

How fast does it dry?

1-2 Days

4-8 Hours

12-24 Hours

12-36 Hours

Risk of mold/mildew

High Risk

Low Risk

Medium Risk

Medium Risk

Can I use cleaning products?

Mild Only

Most Products

Gentle Products

Mild Preferred

Easy to remove stains?

Difficult

Easy

Moderate

Moderate

Can I steam clean?

No

Yes

Not Recommended

No

What if I clean it wrong?

Permanent Damage

Usually Recovers

May Shorten Life

Can Damage Foam

How often to deep clean?

Every 6 months

Every 3-4 months

Every 6 months

Every 4-6 months

Expected lifespan

7-10 years

5-8 years

10-15 years

8-12 years

 

What This Means for Memory Foam Owners

  • Use minimal water: Only spot clean the mattress; never soak or saturate it
  • Stick to gentle cleaners: Baking soda, white vinegar, and mild detergent
  • Plan for long drying: Allow for extended drying times. Before replacing the sheets, let the fans run for 24 to 48 hours
  • Prevent rather than clean: Use a waterproof mattress protector to prevent the requirement for intensive cleaning
  • Act fast on spills: Blot right away; the longer moisture remains, the more difficult it will be to remove
  • Never use steam: The foam structure will be destroyed by heat and moisture combined
A Novilla mattress set with two pillows and a mattress protector, against a light green background

How to Prepare for a Deep Mattress Cleaning

Before you start cleaning your memory foam mattress, spend 15 minutes getting ready. Grab your supplies, set up your space, and check a few things first. This prep work prevents mistakes that could damage your mattress or waste your time. It's quick and simple—and it makes the actual deep mattress cleaning much easier.


Cleaning Supplies Checklist for Memory Foam Mattress

You need specific supplies to clean memory foam safely. Regular household cleaners can ruin the foam, so it's important to use the right stuff. Here's exactly what to get and what to skip. Most items are probably already in your home. Don't forget to have a mattress cover ready for after cleaning.

A collection of cleaning supplies for a memory foam mattress, including a vacuum, baking soda, vinegar, spray bottles, and cloths


Preparation Steps & Best Practices

These eight steps set you up for success. They take about 10-15 minutes total, but they prevent problems like voiding your warranty or damaging the foam. Just follow them in order before you start cleaning.

 

Step What to Do How to Do

1

Check Manufacturer Guidelines

Always review care instructions specific to your mattress brand. Some manufacturers have unique recommendations that can void warranties if not followed precisely.

2

Set Up Work Area

Work in a well-ventilated area with good airflow. Open windows or use fans to promote air circulation during and after cleaning.

3

Strip the Bed

Remove all bedding, mattress protector, and sheets. Wash them separately in hot water while you clean the mattress.

4

Gather All Supplies

Collect all essential tools and cleaning solutions before starting. Having everything ready prevents delays during the cleaning process.

5

Test Cleaning Solution

Test your cleaning solution on a small, inconspicuous area of the mattress first to ensure it doesn't cause discoloration or damage.

6

Inspect the Mattress

Look for specific stains, damage, or areas needing extra attention. Identify the type of stains (protein, liquid, organic) to choose the right cleaning method.

7

Protect Surrounding Area

Use a plastic sheet or drop cloth under and around the mattress to protect your floor from cleaning solutions and moisture.

8

Plan Drying Time

Ensure you have 24-48 hours for the mattress to completely dry before putting bedding back on. Plan accordingly and have alternative sleeping arrangements if needed.


Regular Cleaning Schedule

You don't need to deep clean your memory foam mattress every week. Simple maintenance between deep cleans keeps it fresh and makes the big cleaning jobs easier. Using a quality breathable mattress cover also reduces how often you need to deep clean. Here's what to do and when—most tasks take just a few minutes.

 

How Often What to Do How to Do It

Weekly

Quick Inspection

While changing sheets, take 30 seconds to look for any new stains, spills, or damage that needs immediate attention.

Monthly

Vacuum Mattress Surface

Use your vacuum's upholstery attachment to thoroughly vacuum the entire mattress surface, including seams and edges where dust accumulates.

Monthly

Spot Clean Fresh Stains

Treat any stains immediately with a damp cloth and mild detergent. Blot gently—never rub or scrub the foam.

Every 3-4 Months

Rotate Mattress

Turn the mattress 180 degrees so the head becomes the foot. This ensures even wear and prevents body impressions from forming in one spot.

Every 3-6 Months

Deep Clean

Follow proper memory foam cleaning techniques using baking soda, mild solutions, and adequate drying time (24-48 hours).

Every 3-6 Months

Wash Mattress Protector

Remove your mattress protector and wash it according to manufacturer instructions, typically in hot water.


How to Rotate Your Mattress

Memory foam mattresses have specific rotation requirements that differ from traditional mattresses. Most memory foam mattresses are designed with a specific top and bottom, so you should rotate them but not flip them.


Step-by-Step Rotation Process:

  • Remove all bedding, pillows, and mattress protectors from the bed
  • Carefully rotate the mattress 180 degrees so the head end is now at the foot of the bed
  • Do not flip the mattress over—memory foam mattresses are one-sided and flipping will reduce comfort and support
  • Ensure the mattress sits evenly on your bed frame with no overhanging edges
  • Check that your bed frame provides adequate support across the entire surface to prevent sagging
Dark grey velvet bed frame with channel headboard showcasing the 9-Stronghold Base multi-directional support system.

Why Rotation Matters:

Rotating your mattress every 3-4 months distributes your body weight evenly across the surface. Without rotation, the same areas bear your weight night after night, leading to permanent body impressions and reduced support. Regular rotation helps maintain the mattress's shape and extends its usable life. To understand more about mattress longevity, read our guide on how long a mattress should last.


How to Deep Clean Your Memory Foam Mattress

Deep cleaning a memory foam mattress isn't difficult, but it does require a different approach than cleaning a regular mattress. The key is using minimal moisture and allowing plenty of drying time.
Time needed: About 1-2 hours of active work, plus 24-48 hours for drying. Plan to do this on a day when you have alternative sleeping arrangements.


1. Strip the Bed Completely

Remove everything from your mattress—sheets, mattress protector, pillows, and any toppers. Take all bedding to the washing machine and wash it in hot water (at least 130°F) while you clean the mattress. This kills dust mites and removes allergens.
If possible, move your mattress to a well-ventilated area or at least open all windows in your bedroom. Good airflow is essential for the drying process later.


2. Vacuum Thoroughly

Use your vacuum's upholstery attachment to vacuum the entire mattress surface. Go slowly and methodically, covering every inch. Pay special attention to:
→ All seams and edges where dust collects
→ Any quilted or tufted areas
→ The sides of the mattress
→ Under any handles or logos
This step removes loose dirt, dust, dead skin cells, and dust mites before you start wet cleaning. Don't skip this—it makes the rest of the process much more effective.


3. Spot Clean Stains

Now tackle any visible stains. The cleaning method depends on what caused the stain. Here's what works for different types:


Blood, Sweat, or Body Fluids (Protein Stains)

  • What you need: Cold water, enzyme-free mild detergent, white cloth
  • How to clean: Mix a small amount of detergent with cold water. Dip your cloth in the solution, wring it out well so it's barely damp, and gently blot the stain from the outside edges toward the center. Never rub or scrub. Blot with a dry cloth to remove moisture. Repeat if needed.
  • Why cold water: Hot water sets protein stains permanently.


Urine or Food Stains (Organic Stains)

  • What you need: Baking soda, 3% hydrogen peroxide, spray bottle, white cloth
  • How to clean: First, sprinkle baking soda generously over the stain and let it sit for 30 minutes to absorb moisture and odor. Vacuum it up. Then mix equal parts hydrogen peroxide and water in a spray bottle. Lightly mist the stain (don't soak it), wait 5 minutes, then blot with a dry cloth. The peroxide breaks down organic matter.


Wine, Coffee, or Juice (Liquid Stains)

  • What you need: White vinegar, water, spray bottle, white cloth
  • How to clean: Mix equal parts white vinegar and water in a spray bottle. Lightly spray the stain, then immediately blot with a dry cloth. The vinegar helps break down the stain. Keep blotting with fresh, dry cloths until no more color transfers.

Critical Rule: Always use white cloths for cleaning. Colored cloths can transfer dye to your memory foam mattress. And remember: blot, never rub. Rubbing pushes stains deeper into the foam.


4. Deodorize with Baking Soda

Sprinkle a generous layer of baking soda over the entire mattress surface. You'll need about 1-2 cups for a queen-size mattress. Use your hand to spread it evenly across the entire surface, getting it into seams and crevices.
Let the baking soda sit for at least 8 hours, but 12-24 hours is even better if you can manage it. During this time, baking soda absorbs odors, moisture, and oils from the mattress. If your bedroom gets sunlight, position the mattress so sunlight hits it during this time—UV light naturally kills bacteria and dust mites.
Add 10-15 drops of lavender or tea tree essential oil to your baking soda before sprinkling. Mix it well in a bowl first. This adds a fresh scent and provides natural antimicrobial properties. Don't use more oil than this—too much can leave residue on the foam.


5. Vacuum Again

After the baking soda has sat for at least 8 hours, vacuum it all up using your upholstery attachment. Go over the mattress several times to make sure you've removed all the powder. Check seams and edges carefully—baking soda likes to hide there.
Your memory foam mattress should now smell fresh and clean. If you still notice odors, you can repeat the baking soda treatment.


6. Final Sanitizing Spray (Optional)

For extra freshness and sanitization, make a light vinegar spray. Mix equal parts white vinegar and water in a spray bottle. Very lightly mist the entire mattress surface—you want a fine mist, not wet patches.
The vinegar smell will dissipate as it dries, taking odors with it. This step also helps kill any remaining bacteria or dust mites.

Don't Over-Spray: Use a very light mist. If you can see wet spots or feel dampness when you touch the mattress, you've used too much.


7. Dry Completely

This is the most important step. Your mattress must dry completely before you put any bedding back on. Here's how to ensure thorough drying:
→ Position fans to blow air across the mattress surface. Use multiple fans if you have them.
→ Keep windows open for maximum air circulation.
→ If possible, stand the mattress on its side and rotate it every few hours so air reaches all sides.
→ Avoid direct sunlight or heat sources—these can damage memory foam. Indirect light and air circulation are what you want.
→ Allow a full 24-48 hours for complete drying. It might look dry on the surface but still be damp inside.
To test if it's dry, press your hand firmly on different areas of the mattress. It should feel completely dry and cool to the touch. If any area feels damp or cool, keep drying.

Why Complete Drying Matters: If you put sheets on a damp mattress, you're creating the perfect environment for mold and mildew. These can grow inside the foam where you can't see them, causing health problems and ruining your mattress. Be patient with drying time.


8. Make the Bed with Clean Bedding

Once the mattress is completely dry, put on a clean breathable mattress protector first—this is essential for keeping your mattress clean between deep cleanings. Then add your freshly washed sheets and bedding.
Your mattress is now deeply cleaned, deodorized, and ready for another 3-6 months of use before the next deep clean.
Keep It Clean Longer: Always use a waterproof, breathable mattress protector. It prevents 90% of the stains and damage that would otherwise require deep cleaning. Wash the protector monthly, and you'll rarely need to deep clean your actual mattress.


Why Novilla Mattresses Make Cleaning Easier

Novilla designs mattresses with innovative features that simplify maintenance and support long-term hygiene. Our commitment to eco-friendly materials and thoughtful construction makes cleaning and care more straightforward for users.


ErgoChill Memory Foam Mattress (12")

The ErgoChill Memory Foam Mattress makes cleaning easier with features that resist moisture and dry faster than standard memory foam.
Why It's Easier to Clean:

  • Cool-Touch Nylon Cover – Breathable fabric resists moisture and wipes clean easily.
  • NanoGEL™ Memory Foam – Stays cooler to reduce sweat, so you clean less often.
  • Triple-Layer Design – Better airflow means faster drying after cleaning Durable .
  • Bottom – Handles regular rotation and maintenance without wear.
    Built for Healthy Sleep:
  • OEKO-TEX® certified—safe for skin and free from harmful chemicals.
  • Resists body impressions where dirt and allergens collect.
  • Pet-friendly and durable enough for regular vacuuming.
  • Motion-isolating foam keeps its shape during cleaning.

The cooling design keeps moisture away naturally. That means less chance of mold between cleanings and quicker drying when you do deep clean.


Bliss Memory Foam Mattress (10")

Bliss Memory Foam Mattress provides a perfect balance of comfort and easy maintenance. Its carefully engineered structure supports thorough cleaning and long-term hygiene:

  • Gel-infused memory foam for cooling and easy surface cleaning.
  • Bamboo rayon cover that's naturally breathable.
  • Four-layer structure designed for optimal support and cleaning.
  • CertiPUR-US certified memory foam.
  • Eco-friendly materials that resist dust and allergen accumulation.


Eco-Friendly Maintenance Advantages

Novilla mattresses are designed with cleaning and hygiene in mind:

  • Breathable materials that prevent moisture buildup.
  • Hypoallergenic fabrics that resist dust mites.
  • Easy-to-clean surfaces that maintain mattress integrity.
  • Sustainable manufacturing process supporting overall mattress health.

These features make Novilla mattresses not just comfortable, but also practical for long-term maintenance and cleaning.


Sleep Better, Clean Smarter

Knowing how to clean your memory foam mattress properly makes all the difference. Mattress cleaning doesn't have to be complicated—anyone can learn the right techniques. A consistent care routine helps maintain your mattress's quality and performance. By following these basic steps, you can keep your memory foam mattress in great condition and create a cleaner sleeping environment. For more advice on improving your rest, explore our tips for a healthier sleep routine.

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